Review



mitochondrial reactive oxygen species mtros  (TargetMol)


Bioz Verified Symbol TargetMol is a verified supplier
Bioz Manufacturer Symbol TargetMol manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    TargetMol mitochondrial reactive oxygen species mtros
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitochondrial Reactive Oxygen Species Mtros, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/pmc12134392-69-2-20?v=TargetMol
    Average 94 stars, based on 8 article reviews
    mitochondrial reactive oxygen species mtros - by Bioz Stars, 2026-07
    94/100 stars

    Images

    1) Product Images from "Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis"

    Article Title: Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis

    Journal: Clinical and Translational Medicine

    doi: 10.1002/ctm2.70337

    ISG15 was involved in HG‐induced mitochondrial impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and mtROS (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Figure Legend Snippet: ISG15 was involved in HG‐induced mitochondrial impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and mtROS (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.

    Techniques Used: Western Blot, Expressing, Flow Cytometry, Membrane, Cell Culture



    Similar Products

    mitochondrial reactive oxygen species mtros  (TargetMol)
    94
    TargetMol mitochondrial reactive oxygen species mtros
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitochondrial Reactive Oxygen Species Mtros, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/pmc12134392-69-2-20?v=TargetMol
    Average 94 stars, based on 1 article reviews
    mitochondrial reactive oxygen species mtros - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier
    mitochondrial reactive oxygen species mtros detection  (MedChemExpress)
    97
    MedChemExpress mitochondrial reactive oxygen species mtros detection
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitochondrial Reactive Oxygen Species Mtros Detection, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/pm40188077-191-0-10?v=MedChemExpress
    Average 97 stars, based on 1 article reviews
    mitochondrial reactive oxygen species mtros detection - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    mitochondrial ros detection mitochondrial reactive oxygen species ros levels  (MedChemExpress)
    97
    MedChemExpress mitochondrial ros detection mitochondrial reactive oxygen species ros levels
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitochondrial Ros Detection Mitochondrial Reactive Oxygen Species Ros Levels, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/10__1080_slash_0886022x__2025__2463572-69-0-18?v=MedChemExpress
    Average 97 stars, based on 1 article reviews
    mitochondrial ros detection mitochondrial reactive oxygen species ros levels - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    mitochondrial reactive oxygen species mtros production  (Boster Bio)
    95
    Boster Bio mitochondrial reactive oxygen species mtros production
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitochondrial Reactive Oxygen Species Mtros Production, supplied by Boster Bio, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/pm39313391-47-0-12?v=Boster+Bio
    Average 95 stars, based on 1 article reviews
    mitochondrial reactive oxygen species mtros production - by Bioz Stars, 2026-07
    95/100 stars
    		  Buy from Supplier
    acid mtros mitochondrial reactive oxygen species tca tricarboxylic acid c18  (MedChemExpress)
    94
    MedChemExpress acid mtros mitochondrial reactive oxygen species tca tricarboxylic acid c18
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Acid Mtros Mitochondrial Reactive Oxygen Species Tca Tricarboxylic Acid C18, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/pm37468929-351-15-44?v=MedChemExpress
    Average 94 stars, based on 1 article reviews
    acid mtros mitochondrial reactive oxygen species tca tricarboxylic acid c18 - by Bioz Stars, 2026-07
    94/100 stars
    		  Buy from Supplier
    mitochondrial reactive oxygen species assay mitochondrial ros  (Beijing Solarbio Science)
    97
    Beijing Solarbio Science mitochondrial reactive oxygen species assay mitochondrial ros
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitochondrial Reactive Oxygen Species Assay Mitochondrial Ros, supplied by Beijing Solarbio Science, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/ppr0562007-201-0-16?v=Beijing+Solarbio+Science
    Average 97 stars, based on 1 article reviews
    mitochondrial reactive oxygen species assay mitochondrial ros - by Bioz Stars, 2026-07
    97/100 stars
    		  Buy from Supplier
    mitosox™ red for mitochondrial reactive oxygen species (mtros) assessment  (Thermo Fisher)
    90
    Thermo Fisher mitosox™ red for mitochondrial reactive oxygen species (mtros) assessment
    ISG15 was involved in HG‐induced <t>mitochondrial</t> impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and <t>mtROS</t> (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.
    Mitosox™ Red For Mitochondrial Reactive Oxygen Species (Mtros) Assessment, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mitochondrial+reactive+oxygen+species+mtros/10__1016_slash_j__chemosphere__2018__06__170-43-33-43?v=Thermo+Fisher
    Average 90 stars, based on 1 article reviews
    mitosox™ red for mitochondrial reactive oxygen species (mtros) assessment - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    ISG15 was involved in HG‐induced mitochondrial impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and mtROS (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.

    Journal: Clinical and Translational Medicine

    Article Title: Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis

    doi: 10.1002/ctm2.70337

    Figure Lengend Snippet: ISG15 was involved in HG‐induced mitochondrial impairment and mtDNA release. (A) Representative TEM images of kidney tissues from WT and KO mice treated with STZ ( n = 6). (B) Western blot analysis ISG15/ISGylation expression in TECs treated with vehicle or HG ( n = 3). (C–E) Flow cytometry analysis and quantitative data depicting the mitochondrial membrane potential (C), mitochondrial mass (D) and mtROS (E) ( n = 3). (F and G) qPCR analysis the mtDNA ( Loop1‐3 and mt‐Nd4 ) copy number in the cytosolic compartments (F) and mitochondria (G) ( n = 3). TECs were treated with vehicle or C‐176 (10 µM), and then cultured in HG medium for 48 h. Results are expressed as the mean ± SD. * p < .05; ** p < .01; *** p < .001; ns, not significant.

    Article Snippet: To inhibit mitochondrial reactive oxygen species (mtROS), NLRP3 or STING, cells were pretreated with the mitochondria‐specific antioxidant Mito‐TEMPO (25 μM; TargetMol, China), NLRP3‐specific inhibitor MCC950 (2 μM; TargetMol) or STING‐specific inhibitor C‐176 (10 μM; TargetMol) for 1.5 h before exposure to 40 mM HG.

    Techniques: Western Blot, Expressing, Flow Cytometry, Membrane, Cell Culture